Recombinant Human Chorionic somatomammotropin hormone 2 (CSH2)

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Code CSB-EP006054HU
Size $224
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  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Product Details

Greater than 85% as determined by SDS-PAGE.
Target Names
Uniprot No.
Research Area
Developmental Biology
Alternative Names
Choriomammotropin;Lactogen;Placental lactogen;PL
Homo sapiens (Human)
Expression Region
Target Protein Sequence
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Mol. Weight
53.8 kDa
Protein Length
Full Length of Mature Protein
Tag Info
N-terminal 6xHis-GST-tagged
Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
3-7 business days
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA
Please contact us to get it.

The region for expressing recombinant Human CSH2 contains amino acids 27-217. The theoretical molecular weight of the CSH2 protein is 53.8 kDa. Expression of this CSH2 protein is conducted in e.coli. The CSH2 gene fragment has been modified by fusing the N-terminal 6xHis-GST tag, providing convenience in detecting and purifying the recombinant CSH2 protein during the following stages.

The human chorionic somatomammotropin hormone 2 (CSH2) is a glycoprotein hormone produced by the syncytiotrophoblast cells of the placenta during pregnancy. CSH2 shares structural similarities with growth hormone and prolactin. Its primary function is to regulate maternal metabolism and promote fetal growth by modulating insulin sensitivity and glucose utilization. CSH2 also plays a role in mammary gland development in preparation for lactation. During pregnancy, its levels rise steadily, peaking in the third trimester. The hormone contributes to maintaining a nutrient-rich environment for the developing fetus. Studying CSH2 provides insights into the intricate hormonal regulation crucial for successful pregnancy outcomes.

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Target Background

Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization.
Subcellular Location
Protein Families
Somatotropin/prolactin family
Database Links

HGNC: 2441

OMIM: 118820

KEGG: hsa:1442

STRING: 9606.ENSP00000376623

UniGene: Hs.654390

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