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| Code | CSB-EP006518HU |
| Product Type | Recombinant Protein |
| Size | US$1726 |
| Uniprot No. | P09172 |
| Relevance | Conversion of dopamine to noradrenaline. |
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| Storage Buffer | Tris-based buffer,50% glycerol |
| Alias | Dopamine beta-monooxygenase Cleaved into the following chain: Soluble dopamine beta-hydroxylase |
| Species | Homo sapiens (Human) |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Sequence | SAPRESPLPYHIPLDPEGSLELSWNVSYTQEAIHFQLLVRRLKAGVLFGMSDRGELENADLVVLWTDGDTAYFADAWSDQKGQIHLDPQQDYQLLQVQRTPEGLTLLFKRPFGTCDPKDYLIEDGTVHLVYGILEEPFRSLEAINGSGLQMGLQRVQLLKPNIPEPELPSDACTMEVQAPNIQIPSQETTYWCYIKELPKGFSRHHIIKYEPIVTKGNEALVHHMEVFQCAPEMDSVPHFSGPCDSKMKPDRLNYCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRNDSSGIRLYYTAKLRRFNAGIMELGLVYTPVMAIPPRETAFILTGYCTDKCTQLALPPSGIHIFASQLHTHLTGRKVVTVLVRDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLITSCTYNTEDRELATVGGFGILEEMCVNYVHYYPQTQLELCKSAVDAGFLQKYFHLINRFNNEDVCTCPQASVSQQFTSVPWNSFNRDVLKALYSFAPISMHCNKSSAVRFQGEWNLQPLPKVISTLEEPTPQCPTSQGRSPAGPTVVSIGGGKG |
| Research Area | Neuroscience |
| Source | E.coli |
| Gene Names | DBH |
| Expression Region | 40-617aa |
| Tag Info | N-terminal 6xHis-tagged |
| Mol. Weight | 68.9kDa |
| Protein Description | Full Length of Mature Protein |
| Storage | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
| Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
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| Function | Conversion of dopamine to noradrenaline. |
| Involvement in disease | Dopamine beta-hydroxylase deficiency (DBH deficiency) |
| Subcellular Location | Soluble dopamine beta-hydroxylase: Cytoplasmic vesicle, secretory vesicle lumen, Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen, Secreted, SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle membrane, Single-pass type II membrane protein, Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane, Single-pass type II membrane protein |
| Protein Families | Copper type II ascorbate-dependent monooxygenase family |
| Database Links |
HGNC: 2689 OMIM: 223360 KEGG: hsa:1621 STRING: 9606.ENSP00000376776 UniGene: Hs.591890 |
DBH Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA006518GA01HU | DBH Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA093335 | DBH Antibody | Human | ELISA,WB |
| CSB-PA007654 | DBH Antibody | Human | WB,ELISA |
| CSB-PA020742 | DBH Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA958803 | DBH Antibody | Human,Mouse | ELISA,WB,IHC |
DBH Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP006518HU | Recombinant Human Dopamine beta-hydroxylase(DBH),partial,Yeast | Yeast |
| CSB-CF006518HU | Recombinant Human Dopamine beta-hydroxylase(DBH) | in vitro E.coli expression system |
| CSB-BP006518HU CSB-MP006518HU |
Recombinant Human Dopamine beta-hydroxylase(DBH),partial | Baculovirus Mammalian cell |
DBH ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E09653h | Human dopamine-β-hydroxylase,DBH ELISA Kit | serum, plasma, tissue homogenates | 1.25 ng/mL |
Recombinant Human Ras-related protein Rab-4A(RAB4A)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human Low molecular weight phosphotyrosine protein phosphatase(ACP1)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Rat Dipeptidyl aminopeptidase-like protein 6(Dpp6),partial
Express system: E.coli
Species: Rattus norvegicus (Rat)
Recombinant Mouse Cold-inducible RNA-binding protein(Cirbp)
Express system: E.coli
Species: Mus musculus (Mouse)
