DBH Antibody

Datasheet
Code CSB-PA958803
Size US$299
Uniprot No. P09172
Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA958803(DBH Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse liver tissue, Primary antibody: CSB-PA958803(DBH Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Fusion protein of Human DBH
Raised in Rabbit
Species Reactivity Human,Mouse
Tested Applications ELISA,WB,IHC;ELISA:1:2000-1:5000,WB:1:200-1:1000,IHC:1:50-1:200
Relevance The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide.
Form Liquid
Conjugate Non-conjugated
Storage Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method Antigen affinity purification
Isotype IgG
Alias dopamine beta-hydroxylase (dopamine beta-monooxygenase)
Immunogen Species Homo sapiens (Human)
Target Names DBH
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Conversion of dopamine to noradrenaline.
Involvement in disease Dopamine beta-hydroxylase deficiency (DBH deficiency)
Subcellular Location Soluble dopamine beta-hydroxylase: Cytoplasmic vesicle, secretory vesicle lumen, Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen, Secreted, SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle membrane, Single-pass type II membrane protein, Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane, Single-pass type II membrane protein
Protein Families Copper type II ascorbate-dependent monooxygenase family
Database Links

HGNC: 2689

OMIM: 223360

KEGG: hsa:1621

STRING: 9606.ENSP00000376776

UniGene: Hs.591890

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