Recombinant Human Heme-binding protein 2 (HEBP2)

Code CSB-YP896539HU
MSDS
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Source Yeast
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Code CSB-EP896539HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP896539HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP896539HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
HEBP2
Uniprot No.
Alternative Names
C6orf34; Chromosome 6 open reading frame 34; Hebp2; HEBP2_HUMAN; Heme binding protein 2; Heme-binding protein 2; Placental protein 23; PP23; Protein SOUL; SOUL
Species
Homo sapiens (Human)
Expression Region
2-205
Target Protein Sequence
AEPLQPDPG AAEDAAAQAV ETPGWKAPED AGPQPGSYEI RHYGPAKWVS TSVESMDWDS AIQTGFTKLN SYIQGKNEKE MKIKMTAPVT SYVEPGSGPF SESTITISLY IPSEQQFDPP RPLESDVFIE DRAEMTVFVR SFDGFSSAQK NQEQLLTLAS ILREDGKVFD EKVYYTAGYN SPVKLLNRNN EVWLIQKNEP TKENE
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions.
Gene References into Functions
  1. There are important structural differences in the BH3 domain in the intact SOUL molecule and the same sequence bound to Bcl-xL. PMID: 21639858
  2. SOUL can be a novel member of the BH3 domain-only proteins that cannot induce cell death alone but can facilitate both outer and inner mitochondrial membrane permeabilization and predominantly necrotic cell death in oxidative stress. PMID: 19901022
  3. SOUL promotes necrotic cell death by inducing mitochondrial permeability transition PMID: 17098234
  4. preliminary X ray structure PMID: 19574650
Subcellular Location
Cytoplasm. Mitochondrion.
Protein Families
HEBP family
Tissue Specificity
Detected in placenta.
Database Links

HGNC: 15716

OMIM: 605825

KEGG: hsa:23593

STRING: 9606.ENSP00000058691

UniGene: Hs.486589

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