HEBP2 Antibody

Code CSB-PA010271GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
HEBP2
Alternative Names
C6orf34 antibody; Chromosome 6 open reading frame 34 antibody; Hebp2 antibody; HEBP2_HUMAN antibody; Heme binding protein 2 antibody; Heme-binding protein 2 antibody; Placental protein 23 antibody; PP23 antibody; Protein SOUL antibody; SOUL antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human HEBP2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions.
Gene References into Functions
  1. There are important structural differences in the BH3 domain in the intact SOUL molecule and the same sequence bound to Bcl-xL. PMID: 21639858
  2. SOUL can be a novel member of the BH3 domain-only proteins that cannot induce cell death alone but can facilitate both outer and inner mitochondrial membrane permeabilization and predominantly necrotic cell death in oxidative stress. PMID: 19901022
  3. SOUL promotes necrotic cell death by inducing mitochondrial permeability transition PMID: 17098234
  4. preliminary X ray structure PMID: 19574650
Subcellular Location
Cytoplasm. Mitochondrion.
Protein Families
HEBP family
Tissue Specificity
Detected in placenta.
Database Links

HGNC: 15716

OMIM: 605825

KEGG: hsa:23593

STRING: 9606.ENSP00000058691

UniGene: Hs.486589

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