Recombinant Human Homeobox protein Mohawk (MKX)

Code CSB-YP818257HU
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP818257HU
MSDS
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Source E.coli
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Code CSB-EP818257HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP818257HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP818257HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
MKX
Uniprot No.
Alternative Names
9430023B20Rik; C10orf48; Homeobox protein Mohawk; IFRX; Iroquois family related homeodomain protein; iroquois homeobox protein like 1; IRXL1; MGC39616; MKX; MKX_HUMAN; mohawk homeobox; OTTHUMP00000019374
Species
Homo sapiens (Human)
Expression Region
1-352
Target Protein Sequence
MNTIVFNKLS GAVLFEDGGA SERERGGRPY SGVLDSPHAR PEVGIPDGPP LKDNLGLRHR RTGARQNGGK VRHKRQALQD MARPLKQWLY KHRDNPYPTK TEKILLALGS QMTLVQVSNW FANARRRLKN TVRQPDLSWA LRIKLYNKYV QGNAERLSVS SDDSCSEDGE NPPRTHMNEG GYNTPVHHPV IKSENSVIKA GVRPESRASE DYVAPPKYKS SLLNRYLNDS LRHVMATNTT MMGKTRQRNH SGSFSSNEFE EELVSPSSSE TEGNFVYRTD TLENGSNKGE SAANRKGPSK DDTYWKEINA AMALTNLAQG KDKLQGTTSC IIQKSSHIAE VKTVKVPLVQ QF
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
May act as a morphogenetic regulator of cell adhesion.
Gene References into Functions
  1. Data show that homeobox protein Mohawk (Mkx) is mainly expressed in the outer annulus fibrosus (OAF) of humans and mice. PMID: 27527664
  2. these data shed light on previously unrecognized roles of Mkx in tendinopathy, tenogenesis, and tendon repair as well as in regulating the TGFbeta pathway. PMID: 25332192
  3. Transcription factor Mohawk controls tenogenic differentiation of bone marrow mesenchymal stem cells in vitro and in vivo. PMID: 25312837
  4. Reduced expression of MKX is a feature of degenerated anterior cruciate ligament in osteoarthritis-affected joints. PMID: 23686683
  5. Observational study of gene-disease association. (HuGE Navigator) PMID: 20634891
  6. In silico characterization of the C10orf48 sequence PMID: 16077953

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Subcellular Location
Nucleus.
Protein Families
TALE/IRO homeobox family
Database Links

HGNC: 23729

KEGG: hsa:283078

STRING: 9606.ENSP00000364946

UniGene: Hs.128193

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