Recombinant Human Nucleoside diphosphate kinase 3 (NME3)

Code CSB-YP614400HU
MSDS
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Source Yeast
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Code CSB-EP614400HU
MSDS
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Source E.coli
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Code CSB-EP614400HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP614400HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP614400HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
NME3
Uniprot No.
Alternative Names
c371H6.2; DR-nm23; Expressed in non metastatic cells 3; NDK 3; NDK3; NDK3_HUMAN; NDP kinase 3; NDP kinase C; NDPK C; NDPKC; NM23 H3; nm23-H3; NM23H3; NME 3; NME/NM23 nucleoside diphosphate kinase 3; Nme3; Non metastatic cells 3 protein expressed in; Nucleoside diphosphate kinase 3; Nucleoside diphosphate kinase C
Species
Homo sapiens (Human)
Expression Region
1-169
Target Protein Sequence
MICLVLTIFA NLFPAACTGA HERTFLAVKP DGVQRRLVGE IVRRFERKGF KLVALKLVQA SEELLREHYA ELRERPFYGR LVKYMASGPV VAMVWQGLDV VRTSRALIGA TNPADAPPGT IRGDFCIEVG KNLIHGSDSV ESARREIALW FRADELLCWE DSAGHWLYE
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.
Gene References into Functions
  1. Thus Tip60 interacts with RNR and NME3 to provide site-specific synthesis of dNTP for facilitating DNA repair in serum-deprived cells which contain low levels of dNTPs. PMID: 26945015
  2. Down-regulated DR-nm23 expression is associated with invasion and metastasis in colorectal cancer. PMID: 23765094
  3. Among genes correlated to nodal metastatic progression, we verified in vitro that NM23-H3 reduced cell motility. PMID: 17900511
Protein Families
NDK family
Database Links

HGNC: 7851

OMIM: 601817

KEGG: hsa:4832

STRING: 9606.ENSP00000219302

UniGene: Hs.514065

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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