NME3 Antibody

Code CSB-PA015888GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
NME3
Alternative Names
c371H6.2 antibody; DR-nm23 antibody; Expressed in non metastatic cells 3 antibody; NDK 3 antibody; NDK3 antibody; NDK3_HUMAN antibody; NDP kinase 3 antibody; NDP kinase C antibody; NDPK C antibody; NDPKC antibody; NM23 H3 antibody; nm23-H3 antibody; NM23H3 antibody; NME 3 antibody; NME/NM23 nucleoside diphosphate kinase 3 antibody; Nme3 antibody; Non metastatic cells 3 protein expressed in antibody; Nucleoside diphosphate kinase 3 antibody; Nucleoside diphosphate kinase C antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human NME3
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.
Gene References into Functions
  1. Thus Tip60 interacts with RNR and NME3 to provide site-specific synthesis of dNTP for facilitating DNA repair in serum-deprived cells which contain low levels of dNTPs. PMID: 26945015
  2. Down-regulated DR-nm23 expression is associated with invasion and metastasis in colorectal cancer. PMID: 23765094
  3. Among genes correlated to nodal metastatic progression, we verified in vitro that NM23-H3 reduced cell motility. PMID: 17900511
Protein Families
NDK family
Database Links

HGNC: 7851

OMIM: 601817

KEGG: hsa:4832

STRING: 9606.ENSP00000219302

UniGene: Hs.514065

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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