Code | CSB-EP018207HU |
MSDS | |
Size | $224 |
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This Human PLSCR1 recombinant protein was produced in E.coli, where the gene sequence encoding Human PLSCR1 (1-318aa) was expressed with the N-terminal GST tag. The purity of this PLSCR1 protein was greater than 90% by SDS-PAGE.
PLSCR1 is a phospholipid scramblase, and its primary function is to facilitate the translocation (flipping) of phospholipids on the cell membrane between the inner and outer layers, a process that is typically regulated under normal circumstances. PLSCR1 can expose phospholipids on the cell surface, participating in various biological processes such as cell apoptosis, blood clotting, and immune responses. PLSCR1 is widely distributed in various tissues and cell types, including immune cells, nerve cells, muscle cells, and more. It plays crucial regulatory roles in different biological processes. For example, the activation of PLSCR1 is closely associated with phospholipid externalization during cell apoptosis, cell clotting, immune responses, and more.
PLSCR1 is linked to certain diseases and physiological processes. For instance, it is associated with tumor development and progression, immune system regulation, viral invasion, and more. Aberrant expression of PLSCR1 in certain tumors is related to uncontrolled cell apoptosis and tumor growth. Due to its involvement in various biological processes like cell apoptosis, cancer, and immune regulation, PLSCR1 is of significant interest in medical research. Researchers are exploring the potential applications of PLSCR1 in cancer therapy, immune disease treatment, and the management of inflammatory conditions.
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