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| Code | CSB-YP006400HU |
| Product Type | Recombinant Protein |
| Size |
US$2959Purchase it in Cusabio online store (Shop online in the US. Customers outside the US, please order from local distributors.) |
| Uniprot No. | P08686 |
| Lead Time | 3-7 business days |
| Relevance | Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids. |
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| Storage Buffer | Tris-based buffer,50% glycerol |
| Alias | 21-OHase Cytochrome P-450c21 Cytochrome P450 21 Cytochrome P450 XXI Cytochrome P450-C21 Cytochrome P450-C21B |
| Species | Homo sapiens (Human) |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Sequence | MLLLGLLLLPLLAGARLLWNWWKLRSLHLPPLAPGFLHLLQPDLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTCSIICYLTFGDKIKDDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFFPNPGLRRLKQAIEKRDHIVEMQLRQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALPSLQPLPHCSVILKMQPFQVRLQPRGMGAHSPGQNQ |
| Research Area | Signal Transduction |
| Source | Yeast |
| Gene Names | CYP21A2 |
| Protein Names | Recommended name: Steroid 21-hydroxylase EC= 1.14.99.10 Alternative name(s): 21-OHase Cytochrome P-450c21 Cytochrome P450 21 Cytochrome P450 XXI Cytochrome P450-C21 Cytochrome P450-C21B |
| Expression Region | 1-494aa |
| Tag Info | N-terminal 6xHis-tagged |
| Mol. Weight | 57.9kDa |
| Protein Description | Full Length |
| Storage | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
| Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
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| Function | Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids |
| Involvement in disease | Adrenal hyperplasia 3 (AH3) |
| Subcellular Location | Endoplasmic reticulum membrane, Peripheral membrane protein, Microsome membrane, Peripheral membrane protein |
| Protein Families | Cytochrome P450 family |
| Database Links |
HGNC: 2600 OMIM: 201910 KEGG: hsa:1589 STRING: 9606.ENSP00000408860 UniGene: Hs.654479 |
CYP21A2 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA271449 | CYP21A2 Antibody | Human | ELISA,WB |
| CSB-PA579577 | CYP21A2 Antibody | Human | ELISA,WB |
| CSB-PA007604 | CYP21A2 Antibody | Human | WB,IHC,IF,ELISA |
| CSB-PA007605 | CYP21A2 Antibody | Human | WB,IHC,ELISA |
| CSB-PA007610 | CYP21A2 Antibody | Human | WB,ELISA |
| CSB-PA263571 | CYP21A2 Antibody | Human | ELISA,IHC |
| CSB-PA891037 | CYP21A2 Antibody | Human | ELISA,WB,IHC |
| CSB-PA006400LB01HU | CYP21A2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA006400LC01HU | CYP21A2 Antibody, FITC conjugated | Human | ELISA |
| CSB-PA006400LD01HU | CYP21A2 Antibody, Biotin conjugated | Human | ELISA |
CYP21A2 Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA006400LA01HU | CYP21A2 Antibody | Human | ELISA, WB, IHC, IF |
CYP21A2 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-EP006400HUe0 | Recombinant Human Steroid 21-hydroxylase(CYP21A2) | E.coli |
| CSB-EP006400HU | Recombinant Human Steroid 21-hydroxylase(CYP21A2) | E.coli |
| CSB-BP006400HU CSB-MP006400HU |
Recombinant Human Steroid 21-hydroxylase(CYP21A2) | Baculovirus Mammalian cell |
CYP21A2 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E09977h | Human Cytochrome P450c21/21-hydroxylase,CYP21A ELISA Kit | serum, plasma, cell lysates, tissue homogenates | 0.39 ng/mL |
Recombinant Human Glutathione peroxidase 1(GPX1)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Mouse Lysyl oxidase homolog 1(Loxl1)
Express system: Yeast
Species: Mus musculus (Mouse)
Recombinant Human Ras-related protein Ral-B(RALB)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human Matrix metalloproteinase-9(MMP9) ,partial
Express system: Yeast
Species: Homo sapiens (Human)
