Recombinant Human Substance-P receptor(TACR1),partial

In Stock
Code CSB-EP023068HU
Product Type Recombinant Protein
Size US$1726
Uniprot No. P25103
Relevance This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger syst. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Storage Buffer Tris-based buffer,50% glycerol
Alias NK-1 receptor ;NK-1RTachykinin receptor 1
Species Homo sapiens (Human)
Purity Greater than 90% as determined by SDS-PAGE.
Sequence MDNVLPVDSDLSPNISTNTSEPNQFVQPA
Research Area Neuroscience
Source E.coli
Gene Names TACR1
Expression Region 1-29aa
Tag Info N-terminal GST-tagged
Mol. Weight 30.1kDa
Protein Description Partial
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is
Subcellular Location Cell membrane, Multi-pass membrane protein
Protein Families G-protein coupled receptor 1 family
Database Links

HGNC: 11526

OMIM: 162323

KEGG: hsa:6869

STRING: 9606.ENSP00000303522

UniGene: Hs.633301

Pathway Calcium signaling pathway

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