Recombinant Human Uncharacterized protein C19orf52 (C19orf52)

Code CSB-YP883591HU
MSDS
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Source Yeast
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Code CSB-EP883591HU
MSDS
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Source E.coli
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Code CSB-EP883591HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP883591HU
MSDS
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Source Baculovirus
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Code CSB-MP883591HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
TIMM29
Uniprot No.
Alternative Names
C19orf52; Chromosome 19 open reading frame 52; CS052_HUMAN; Uncharacterized protein C19orf52
Species
Homo sapiens (Human)
Expression Region
1-260
Target Protein Sequence
MAAAALRRFW SRRRAEAGDA VVAKPGVWAR LGSWARALLR DYAEACRDAS AEARARPGRA AVYVGLLGGA AACFTLAPSE GAFEEALLEA SGTLLLLAPA TRNRESEAFV QRLLWLRGRG RLRYVNLGLC SLVYEAPFDA QASLYQARCR YLQPRWTDFP GRVLDVGFVG RWWVLGAWMR DCDINDDEFL HLPAHLRVVG PQQLHSETNE RLFDEKYKPV VLTDDQVDQA LWEEQVLQKE KKDRLALSQA HSLVQAEAPR
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force. Required for the stability of the TIM22 complex and functions in the assembly of the TIMM22 protein into the TIM22 complex. May facilitate cooperation between TIM22 and TOM complexes by interacting with TOMM40.
Gene References into Functions
  1. Here, the authors identify Tim29 (C19orf52) as a novel, metazoan-specific subunit of the human TIM22 complex. The protein is integrated into the mitochondrial inner membrane with it's C-terminus exposed to the intermembrane space. PMID: 27554484
  2. TIM29 is required for the structural integrity of the TIM22 complex and for import of substrate proteins by the carrier translocase PMID: 27718247
Subcellular Location
Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side.
Database Links

HGNC: 25152

OMIM: 617380

KEGG: hsa:90580

STRING: 9606.ENSP00000270502

UniGene: Hs.164026

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