Recombinant Human Zinc finger protein 410 (ZNF410)

Code CSB-YP026730HU
MSDS
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Source Yeast
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Code CSB-EP026730HU
MSDS
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Source E.coli
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Code CSB-EP026730HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP026730HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP026730HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
ZNF410
Uniprot No.
Alternative Names
Another partner for ARF 1; APA 1; APA1; Clones 23667 and 23775 zinc finger protein; D12Ertd748e; Zfp410; Zinc finger protein 410; Zinc finger protein APA 1; Zinc finger protein APA-1; ZN410_HUMAN; Znf410
Species
Homo sapiens (Human)
Expression Region
1-478
Target Protein Sequence
MLSDELESKP ELLVQFVQNT SIPLGQGLVE SEAKDITCLS LLPVTEASEC SRLMLPDDTT NHSNSSKEVP SSAVLRSLRV NVGPDGEETR AQTVQKSPEF LSTSESSSLL QDLQPSDSTS FILLNLTRAG LGSSAEHLVF VQDEAEDSGN DFLSSESTDS SIPWFLRVQE LAHDSLIAAT RAQLAKNAKT SSNGENVHLG SGDGQSKDSG PLPQVEKKLK CTVEGCDRTF VWPAHFKYHL KTHRNDRSFI CPAEGCGKSF YVLQRLKVHM RTHNGEKPFM CHESGCGKQF TTAGNLKNHR RIHTGEKPFL CEAQGCGRSF AEYSSLRKHL VVHSGEKPHQ CQVCGKTFSQ SGSRNVHMRK HHLQLGAAGS QEQEQTAEPL MGSSLLEEAS VPSKNLVSMN SQPSLGGESL NLPNTNSILG VDDEVLAEGS PRSLSSVPDV THHLVTMQSG RQSYEVSVLT AVNPQELLNQ GDLTERRT
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Transcription factor that binds to the sequence motif 5'-CATCCCATAATA-3' in regulatory elements and modulates transcription of target genes. Indirectly represses transcription of HBG1 and HBG2, hemoglobin subunits gamma-1 and gamma-2, in erythroid cells, via direct transcriptional activation of the chromodomain protein CHD4, a component of the NuRD complex. Activates transcription of matrix-remodeling genes such as MMP1 during fibroblast senescence. Activates transcription of the gap junction gene GJC1, perhaps in response to increasing glucose.
Gene References into Functions
  1. No association was found between Apa1 genotypes and osteoporosis PMID: 26290023
  2. APA1 has a role in inducing extracellular matrix remodeling genes PMID: 12370286
  3. VDR polymorphism genotypes and haplotypes did not directly alter recurrence risk, but the reduction in risk associated with high dairy product intake was confined to individuals with ApaI aA/AA genotype. PMID: 18470879
Subcellular Location
Nucleus.
Tissue Specificity
Widely expressed.
Database Links

HGNC: 20144

KEGG: hsa:57862

STRING: 9606.ENSP00000407130

UniGene: Hs.270869

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