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Recombinant Location of vulva defective 1 (lov-1), partial

Recombinant Location of vulva defective 1 (lov-1), partial

Code	CSB-YP600254CXY
MSDS	MSDS Datasheet
Size	Pls inquire
Source	Yeast
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Code	CSB-EP600254CXY
MSDS	MSDS Datasheet
Size	Pls inquire
Source	E.coli
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Code	CSB-EP600254CXY-B
MSDS	MSDS Datasheet
Size	Pls inquire
Source	E.coli
Conjugate	Avi-tag Biotinylated E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code	CSB-BP600254CXY
MSDS	MSDS Datasheet
Size	Pls inquire
Source	Baculovirus
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Code	CSB-MP600254CXY
MSDS	MSDS Datasheet
Size	Pls inquire
Source	Mammalian cell
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

lov-1

Uniprot No.

Q09624

Alternative Names

lov-1; pkd-1; ZK945.9/ZK945.10; Location of vulva defective 1; Polycystic kidney disease 1 protein homolog; Polycystin-1

Species

Caenorhabditis elegans

Protein Length

Partial

Tag Info

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Form

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer before Lyophilization

Tris/PBS-based buffer, 6% Trehalose.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet

Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function

Required for two aspects of male mating behavior: response to hermaphrodite contact and vulva location. Acts in the same pathway as pkd-2 and atp-2 in response behavior. May be required for ciliary targeting of pkd-2.

Gene References into Functions

expressed in male-specific neurons, required for mating PMID: 26702651
These data reveal that the STAM-Hrs complex, which down-regulates ligand-activated growth factor receptors from the cell surface of yeast and mammalian cells, also regulates the localization and signaling of a ciliary PC1 receptor-TRPP2 complex. PMID: 17581863
lov-1 is required for two male sensory behaviors: response and vulva location. It is a close homolog of human PKD1 and is localized in the same neurons as worm PKD-2, suggesting a common pathway. PMID: 10517638

Subcellular Location

Membrane; Multi-pass membrane protein. Cell projection, cilium. Note=localizes to both the ciliary base and cilium proper.

Protein Families

Polycystin family

Tissue Specificity

Exclusively expressed in a subset of three categories of adult male sensory neurons: ray neurons, hook neurons and head cephalic (CEM) neurons.

Database Links

KEGG: cel:CELE_ZK945.9

STRING: 6239.ZK945.9

UniGene: Cel.36423

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