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Recombinant Mechanosensory abnormality protein 6 (mec-6), partial

Recombinant Mechanosensory abnormality protein 6 (mec-6), partial

Code	CSB-YP519039CXY
MSDS	MSDS Datasheet
Size	Pls inquire
Source	Yeast
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Code	CSB-EP519039CXY
MSDS	MSDS Datasheet
Size	Pls inquire
Source	E.coli
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Code	CSB-EP519039CXY-B
MSDS	MSDS Datasheet
Size	Pls inquire
Source	E.coli
Conjugate	Avi-tag Biotinylated E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code	CSB-BP519039CXY
MSDS	MSDS Datasheet
Size	Pls inquire
Source	Baculovirus
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Code	CSB-MP519039CXY
MSDS	MSDS Datasheet
Size	Pls inquire
Source	Mammalian cell
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

mec-6

Uniprot No.

O01811

Alternative Names

mec-6; W02D3.3Mechanosensory abnormality protein 6

Species

Caenorhabditis elegans

Protein Length

Partial

Tag Info

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Form

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer before Lyophilization

Tris/PBS-based buffer, 6% Trehalose.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet

Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function

Subunit of an amiloride-sensitive cation channel (degenerin channel complex) permeable for sodium, potassium, lithium and N-methylglucamine, and required for mechanosensory transduction (touch sensitivity). Interacts with degenerin channel proteins and stabilizes the channel. Plays a role in mechanosensory transduction (touch sensitivity).

Gene References into Functions

MEC-6 and POML-1 interact with MEC-4 to facilitate expression and localization of MEC-4 on the cell surface. Thus MEC-6 and POML-1 act more like chaperones for MEC-4 than channel components. PMID: 26941331
MEC-10, but not MEC-6, forms puncta in touch receptor neurites that colocalize with MEC-4 when MEC-4 is overexpressed in the touch receptor neurons PMID: 26324944
we show that mec-6 encodes a single-pass membrane-spanning protein with limited similarity to paraoxonases; mechanosensory protein MEC-6 is a subunit of the C. elegans touch-cell degenerin channel PMID: 12478294

Subcellular Location

Cell membrane; Single-pass membrane protein. Cell projection, axon.

Protein Families

Paraoxonase family

Tissue Specificity

Expressed in neurons including the six touch receptors, ventral cord motor neurons, HSN, PVD, PVC, IL1, and several neurons near the nerve ring, in the anal ganglion and in the male tail sensory rays, in muscles including the body wall, vulval, intestinal

Database Links

KEGG: cel:CELE_W02D3.3

STRING: 6239.W02D3.3

UniGene: Cel.197

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