Recombinant Mouse Meteorin(Metrn)

Code CSB-YP805389MO
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Source Yeast
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Code CSB-EP805389MO
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Source E.coli
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Code CSB-EP805389MO-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP805389MO
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Source Baculovirus
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Code CSB-MP805389MO
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Source Mammalian cell
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Product Details

Purity >85% (SDS-PAGE)
Target Names Metrn
Uniprot No. Q8C1Q4
Alternative Names Metrn; Hyrac; Meteorin; Hypoxia/reoxygenation regulatory factor
Species Mus musculus (Mouse)
Expression Region 22-291
Target Protein Sequence GYSEDRCSW RGSGLTQEPG SVGQLTLDCT EGAIEWLYPA GALRLTLGGP DPGTRPSIVC LRPERPFAGA QVFAERMTGN LELLLAEGPD LAGGRCMRWG PRERRALFLQ ATPHRDISRR VAAFRFELHE DQRAEMSPQA QGLGVDGACR PCSDAELLLA ACTSDFVIHG TIHGVAHDTE LQESVITVVV ARVIRQTLPL FKEGSSEGQG RASIRTLLRC GVRPGPGSFL FMGWSRFGEA WLGCAPRFQE FSRVYSAALT THLNPCEMAL D
Protein Length Full Length of Mature Protein
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting
and FAQs
Protein FAQs
Storage Condition Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

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Target Data

Function Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia.
Gene References into Functions
  1. Meteorin is a novel regulator of Nodal transcription PMID: 24558432
  2. Recombinant Metrn infused into the stroke-damaged brain stimulates cell proliferation in subventricular zone, promotes neuroblast migration, and increases the number of immature and mature neurons in the ischemic striatum. PMID: 22044868
  3. promotes both cortical stem cell differentiation and retinal glia development via Jak-STAT3 pathway PMID: 20460434
  4. Data show that Meteorin is expressed in the central nervous system both during development and in adult mice. PMID: 19259827
Subcellular Location Secreted
Protein Families Meteorin family
Tissue Specificity Highly expressed in brain. Expressed in undifferentiated neural progenitors and in astrocyte lineage, particulary in Bergmann glia, a subtype of radial glia, and a few discrete neuronal populations residing in the superior colliculus, the ocular motor nuc
Database Links

KEGG: mmu:70083

STRING: 10090.ENSMUSP00000002344

UniGene: Mm.41925

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