Recombinant Mouse Platelet endothelial aggregation receptor 1 (Pear1), partial

In Stock
Code CSB-EP017765MO4
MSDS
Size $306
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  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Product Details

Purity
Greater than 95% as determined by SDS-PAGE.
Activity
Not Test
Target Names
Pear1
Uniprot No.
Research Area
Cardiovascular
Alternative Names
mPEAR1;Jagged and Delta protein;Protein Jedi;Multiple epidermal growth factor-like domains protein 12;Multiple EGF-like domains protein 12
Species
Mus musculus (Mouse)
Source
E.coli
Expression Region
776-1034aa
Target Protein Sequence
GYRQWQKGKEHEHLAVAYSTGRLDGSDYVMPDVSPSYSHYYSNPSYHTLSQCSPNPPPPNKVPGSQLFVSSQAPERPSRAHGRENHVTLPADWKHRREPHERGASHLDRSYSCSYSHRNGPGPFCHKGPISEEGLGASVMSLSSENPYATIRDLPSLPGEPRESGYVEMKGPPSVSPPRQSLHLRDRQQRQLQPQRDSGTYEQPSPLSHNEESLGSTPPLPPGLPPGHYDSPKNSHIPGHYDLPPVRHPPSPPSRRQDR
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Mol. Weight
32.9 kDa
Protein Length
Partial
Tag Info
N-terminal 6xHis-tagged
Form
Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
3-7 business days
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Datasheet & COA
Please contact us to get it.

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Target Background

Function
When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells.
Gene References into Functions
  1. Platelet endothelial aggregation receptor-1: a novel modifier of neoangiogenesis. PMID: 26156496
  2. Jedi is involved in the fine regulation of the early stages of hematopoietic differentiation, presumably through the Notch signaling pathway. PMID: 17226770
  3. a cellular and molecular mechanism by which neuronal corpses are culled during dorsal root ganglia development involves Jedi protein PMID: 19915564
Subcellular Location
Cell membrane; Single-pass membrane protein.
Protein Families
MEGF family
Tissue Specificity
Expressed in thymocytes, bone marrow stromal and osteogenic cells (at protein level). Strongly expressed in kidney and heart. Moderately expressed in lung, spleen, thymus, liver, brain, testis, skin and stomach. Expressed in hematopoietic stem progenitor
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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