Recombinant Mouse Receptor-type tyrosine-protein phosphatase delta (Ptprd), partial

Product Details

Purity

≥85% (SDS-PAGE)

Target Names

Ptprd

Uniprot No.

Q64487

Alternative Names

Ptprd; Receptor-type tyrosine-protein phosphatase delta; Protein-tyrosine phosphatase delta; R-PTP-delta; EC 3.1.3.48

Species

Mus musculus (Mouse)

Protein Length

Partial

Tag Info

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Form

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer before Lyophilization

Tris/PBS-based buffer, 6% Trehalose.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet

Please contact us to get it.

Customer Reviews and Q&A

■ Customer Reviews

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■ Q&A

I'd like to know if this product is available. I would also like to confirm that the recombinant protein being expressed is the extracellular domain of PTPRD.

Thanks for your inquiry，The product details is as below.
This protein is the Tyrosine-protein phosphatase 2 Domain of mouse PTPRD.
Recombinant Mouse Receptor-type tyrosine-protein phosphatase delta(Ptprd) ,partial
CSB-YP727073MO >> Yeast
CSB-EP727073MO >> E.coli
CSB-BP727073MO >> Baculovirus
CSB-MP727073MO >> Mammalian cell working days
Expression Region: 1644-1903aa; C-terminal fragment; Tyrosine-protein phosphatase 2 Domain
Tag Info: YP: N-terminal 6xHis-tag; EP, BP, MP: N-terminal 10xHis-tag and C-terminal Myc-tag
Target Protein Sequence:

MELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEY

Target Background

Function

Can bidirectionally induce pre- and post-synaptic differentiation of neurons by mediating interaction with IL1RAP and IL1RAPL1 trans-synaptically. Involved in pre-synaptic differentiation through interaction with SLITRK2.

Gene References into Functions

Chondroitin Sulfate Proteoglycans Negatively Modulate Spinal Cord Neural Precursor Cells by Signaling Through LAR and RPTPsigma and Modulation of the Rho/ROCK Pathway. PMID: 25703008
Ptprd is a tumor suppressor that can promote tumorigenesis in concert with Cdkn2a loss. PMID: 25138050
We reveal that PTPRD is a bona fide tumor suppressor, pinpoint PTPRD loss as a cause of aberrant STAT3 activation in gliomas, and establish PTPRD loss, in the setting of CDKN2A/p16(INK4A) deletion, as a driver of glioma progression. PMID: 24843164
RPTP-sigma and RPTP-delta complement each other functionally during mammalian development, and reveal an essential contribution of RPTP-sigma and RPTP-delta to appropriate motoneuron axon targeting during mammalian axonogenesis. PMID: 16738228
Receptor protein tyrosine phosphatase-delta cooperates with hedgehog-responsive gene MIM to induce cytoskeletal remodeling. PMID: 15684034
PTPRD may be one of a select group of tumor suppressor genes that are inactivated in a wide range of common tumor types. PMID: 19074898

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Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Families

Protein-tyrosine phosphatase family, Receptor class 2A subfamily

Tissue Specificity

Brain, kidney, heart, and some B-cell lines.

Database Links

KEGG: mmu:19266

STRING: 10090.ENSMUSP00000133468

UniGene: Mm.184021

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Code	CSB-YP727073MO
MSDS	MSDS Datasheet
Size	Pls inquire
Source	Yeast
Have Questions?	Leave a Message or Start an on-line Chat

Code	CSB-EP727073MO
MSDS	MSDS Datasheet
Size	Pls inquire
Source	E.coli
Have Questions?	Leave a Message or Start an on-line Chat

Code	CSB-EP727073MO-B
MSDS	MSDS Datasheet
Size	Pls inquire
Source	E.coli
Conjugate	Avi-tag Biotinylated E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
Have Questions?	Leave a Message or Start an on-line Chat

Code	CSB-BP727073MO
MSDS	MSDS Datasheet
Size	Pls inquire
Source	Baculovirus
Have Questions?	Leave a Message or Start an on-line Chat

Code	CSB-MP727073MO
MSDS	MSDS Datasheet
Size	Pls inquire
Source	Mammalian cell
Have Questions?	Leave a Message or Start an on-line Chat

Recombinant Mouse Receptor-type tyrosine-protein phosphatase delta (Ptprd), partial

Product Details

Customer Reviews and Q&A

Target Background

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