Recombinant Mouse UMP-CMP kinase(Cmpk1)

Code CSB-EP875274MOa2
Product Type Recombinant Protein
Size US$2466
Uniprot No. Q9DBP5
Relevance Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Storage Buffer Tris-based buffer,50% glycerol
Alias Deoxycytidylate kinaseUniRule annotation Short name: CKUniRule annotation Short name: dCMP kinaseUniRule annotation Nucleoside-diphosphate kinaseUniRule annotation (EC:2.7.4.6UniRule annotation) Uridine monophosphate/cytidine monophosphate kinaseUniRule annotation Short name: UMP/CMP kinaseUniRule annotation Short name: UMP/CMPK
Species Mus musculus (Mouse)
Purity Greater than 90% as determined by SDS-PAGE.
Sequence MKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLESTKPIIDLYEEMGKVKKIDASKSVDEVFGEVVKIFDKEG
Research Area Epigenetics and Nuclear Signaling
Source E.coli
Gene Names Cmpk1
Expression Region 1-196aa
Tag Info N-terminal 6xHis-SUMO-tagged
Mol. Weight 38.2kDa
Protein Description Full Length
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
Subcellular Location Nucleus, Cytoplasm
Protein Families Adenylate kinase family, UMP-CMP kinase subfamily
Database Links

KEGG: mmu:66588

STRING: 10090.ENSMUSP00000030491

UniGene: Mm.294159

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