Recombinant Protein male abnormal 3 (mab-3)

Code CSB-YP522723CXY
MSDS
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Source Yeast
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Code CSB-EP522723CXY
MSDS
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Source E.coli
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Code CSB-EP522723CXY-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP522723CXY
MSDS
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Source Baculovirus
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Code CSB-MP522723CXY
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
mab-3
Uniprot No.
Alternative Names
mab-3; Y53C12B.5; Protein male abnormal 3
Species
Caenorhabditis elegans
Expression Region
1-290
Target Protein Sequence
MLTEDPVSEI CEAKAVDELA EQEKNYYCQR CLNHGELKPR KGHKPDCRYL KCPCRECTMV EQRRQLNNLL SKKKIHCTPA TQTRDGKRVR DPHCARCSAH GVLVPLRGHK RTMCQFVTCE CTLCTLVEHR RNLMAAQIKL RRSQQKSRDG KEPKRNSRRK SKDMDMEMMV VTATDGQKII GTSASPSPSS TTDTMSPSLS MSPPCSPSPL LAQYTLTLAA PIPIYPPIPM NQQLISLQQQ QFLMSIIQNM APSIGQQAPL LPGISAGSVS SAAILNEFWS MYLKNYGLQA
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Transcription factor which binds the DNA motif 5'-[CGA][TCA][TA]ACAATGT[AT][TGA]C-3', probably as a monomer. Acts partially redundantly with the transcription factor dmd-3 to coordinate tail tip cell fusion and retraction and thereby regulate male tail tip morphogenesis. Promotes male-specific development of two tissues, the peripheral nervous system and the intestine. In the peripheral nervous system, directs differentiation of sensory ray neuroblasts into peripheral sense organs. In the intestine, causes repression of vitellogenin gene transcription.
Gene References into Functions
  1. MAB-3 regulates oxidative stress sensitivity by repressing transcription of ELT-2 target genes in the intestine. PMID: 20498281
  2. mab-3 is suppressed by the mutants of mes-2, mes-3, and mes-6. PMID: 12791262
  3. mab-3 is suppressed by mutants of mes-2, mes-3, and mes-6. PMID: 12791273
Subcellular Location
Nucleus.
Tissue Specificity
Expression is undetectable in hermaphrodites, but persists in males. In males, expressed in cells of the tail tip.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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