Recombinant Rat Protein-arginine deiminase type-2 (Padi2)

Code CSB-YP017377RA
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP017377RA
MSDS
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Source E.coli
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Code CSB-EP017377RA-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP017377RA
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP017377RA
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Padi2
Uniprot No.
Alternative Names
Padi2; Pad2; Pdi; Pdi2; Protein-arginine deiminase type-2; EC 3.5.3.15; Peptidylarginine deiminase II; Protein-arginine deiminase type II
Species
Rattus norvegicus (Rat)
Expression Region
1-665
Target Protein Sequence
MLRERTVRLQ YGSRVEAVYV LGTQLWTDVY SAAPAGAKTF SLKHSEGVKV EVVRDGEAEE VVTNGKQRWA LSPSTTLRLS MAQASTEASS DKVTVNYYEE DGSAPIDQAG LFLTAIEISL DVDADRDGEV EKNNPKKASW TWGPEGQGAI LLVNCDRDTP WLPKEDCSDE KVYSKQDLQD MSQMILRTKG PDRLPAGYEI VLYISMSDSD KVGVFYVENP FFGQRYIHIL GRQKLYHVVK YTGGSAELLF FVEGLRFPDE SFSGLVSIHV SLLEYMAEDI PLTPIFTDTV TFRIAPWIMT PNILPPVSVF VCCMKDNYLF LKEVKNLVEK TNCELKVCFQ YMNRGDRWIQ DEIEFGYIEA PHKGFPVVLD SPRDGNLKDF PIKQLLGPDF GYVTREPLFE TVTSLDSFGN LEVSPPVTVN GKAYPLGRIL IGSSFPLSGG RRMTKVVRDF LQAQQVQAPV ELYSDWLTVG HVDEFMTFVP IPGKKEFRLL MASTSACYQL FREKQKEGHG EAIMFKGLGG MSSKRITINK ILSNESLTQE NQYFQRCLDW NRDILKKELA LTEKDIIDLP ALFKMDEDRQ ARAFFPNMVN MIVLDKDLGI PKPFGPQVEE ECCLETHVRG LLEPLGLACT FIDDISAYHK FLGEVHCGTN VRRKPFTFKW WHMVP
Protein Length
Full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Catalyzes the deimination of arginine residues of proteins.
Gene References into Functions
  1. This report revealed the expression of PAD2 by microglia in the prenatal cerebrum at embryonic stages E19-E21. PMID: 17579814
  2. The reduced levels of deimination commensurate with reduced protein, mRNA and activity of peptidylarginine deiminase type 2 in the retina. PMID: 18248664
  3. Mechanical stretching induced PAD2 expression and consequent protein deimination. PMID: 19085382
  4. These biochemical and immunohistochemical results suggest that PAD2 might play an important role in the pathology of early Alzheimer's disease PMID: 19641855
Subcellular Location
Cytoplasm.
Protein Families
Protein arginine deiminase family
Tissue Specificity
Spinal cord, submaxillary gland, cerebrum, cerebellum, and skeletal muscle.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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