Recombinant Saccharomyces cerevisiae Ubiquitin-like protein SMT3 (SMT3)

Ubiquitin-like protein SMT3 CSB-YP615489SVG is a recombinant Saccharomyces cerevisiae full-length of mature SMT3 protein containing amino acid residues of 2-98. It is produced in the yeast cells through Eukaryotic expression and fused with a 6xHis-tag at the N-terminus. And it has high purity of up to 90% determined by SDS-PAGE. Its predicted molecular weight is 13.1 kDa, but the actual observed molecular mass via SDS-PAGE analysis is slightly higher due to post-transcriptional modifications such as glycosylation. This recombinant SMT3 protein is in-stock, allowing for continuous sourcing and eliminating the intermediate waiting periods for protein preparation. This SMT3 protein not only acts as an immunogen for antibody production but also finds uses in the studies of microbiology.

SMT3 is the only small ubiquitin-like modifier (SUMO) protein of Saccharomyces cerevisiae. Like ubiquitin, SMT3 consists of multiple lysine residues that could serve as sites for synthesis of topologically and functionally distinct chains. TongLiu etc. demonstrated that SMT3 plays critical roles in the asexual development, environmental adaptation, and pathogenicity of Beauveria bassiana.