Code | CSB-RA005267A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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IHC | 1:50-1:200 |
This is a recombinant monoclonal antibody against CETP. It is matched isotype control by rabbit IgG. The cloning of the human CETP DNA gene into the vector and subsequent transfection into the cell line for in vitro expression lead to the production of this CETP antibody. This CETP antibody can recognize human CETP protein. It is purified using affinity-chromatography and is recommended for ELISA and IHC applications.
CETP is an enzyme responsible for moving cholesterol esters and triglycerides between VLDL, LDL, and HDL. It, therefore, plays an important role in blood lipid homeostasis. Plasma CETP results in free cholesterol accumulation on islets, contributing to beta-cell dysfunction. CETP inhibition thus could be a new protective strategy for dyslipidemia associated with diabetes and obesity.
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