Code | CSB-RA207775A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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WB | 1:500-1:5000 |
FLI1, a member of the Ets family, is expressed in fibroblasts, endothelial cells, and immune cells. FLI1 gene is involved in the development, proliferation, activation, migration, and other processes of immune cells. FLI1 can also affect the function of immune cells by regulating cytokines and chemokines. Emerging evidence has shown that FLI1 is implicated in the etiology of several autoimmune diseases, including systemic sclerosis (SSc) and systemic lupus erythematosus (SLE). Abnormal expression of the FLI1 transcription factor following genetic mutations has been considered a seminal event in the initiation of certain types of malignant transformation and tumor progression.
The production of this recombinant FLI1 antibody started with immunization. And then the workflow included B cell harvest and enrichment; import single B cell; assays to identify the specificity, affinity & functionality of the cell; export the single B cell; cDNA synthesis and sequencing; express the FLI1 antibody in mammalian cells. The target FLI1 antibody was validated in ELISA, WB.There are currently no reviews for this product.