Code | CSB-RA229992A0HU |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
WB | 1:500-1:5000 |
IHC | 1:50-1:200 |
LRG1 is a secreted member of the family of leucine-rich repeat (LRR) proteins involved in vascular dysfunction, inflammation, pathological angiogenesis, and fibrosis. Under physiological conditions, LRG1 is constitutively expressed by the liver and granulocytes. LRG1 has been implicated in a variety of cancers, inflammation, pathogenic angiogenesis, lymphocyte differentiation, and neutrophil function. A substantial increase in LRG1 expression has been reported in cancer and diabetes, but also in infections, cardiovascular, kidney, lung, neurological, and autoimmune disorders.
The production of this recombinant LRG1 antibody was carried out in vitro. It began with immunization of animals so that the B cells could be obtained. The next step was selection of B cells. The positive cells would be screened out for the next step, single B cell antibody sequencing and cloning. Once the LRG1 antibody sequence was obtained, it would be inserted into a plasmid, which could be transfected into mammalian cells for the expression of LRG1 antibody.There are currently no reviews for this product.