Code | CSB-RA007523A51phHU |
Size | US$350 |
Image |
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Uniprot No. | P05198 | ||||||||
Target Names | EIF2S1 | ||||||||
Alternative Names | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, eIF-2A, eIF-2alpha, EIF2S1, EIF2A | ||||||||
Species Reactivity | Human | ||||||||
Immunogen | A synthesized peptide derived from Human Phospho-EIF2S1 (S51) | ||||||||
Immunogen Species | Homo sapiens (Human) | ||||||||
Conjugate | Non-conjugated | ||||||||
Clonality | Monoclonal | ||||||||
Isotype | Rabbit IgG | ||||||||
Purification Method | Affinity-chromatography | ||||||||
Concentration | It differs from different batches. Please contact us to confirm it. | ||||||||
Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | ||||||||
Form | Liquid | ||||||||
Tested Applications | ELISA, WB, IHC, IF | ||||||||
Recommended Dilution |
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Protocols | ELISA Protocol Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol Immunofluorescence (IF) Protocol |
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Troubleshooting and FAQs | Antibody FAQs | ||||||||
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||||||
Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. | ||||||||
Still Have Questions? | Leave a Message or Start an on-line Chat |
Function | Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B. |
Subcellular Location | Cytoplasm, Stress granule |
Protein Families | EIF-2-alpha family |
Database Links |
HGNC: 3265 OMIM: 603907 KEGG: hsa:1965 STRING: 9606.ENSP00000256383 UniGene: Hs.151777 |
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