RAVER2 Recombinant Monoclonal Antibody

Code CSB-RA860264A0HU
Size US$210
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Image
  • Flow cytometric analysis of RAVER2 expression in HeLa cells using RAVER2 antibody. Green, isotype control; red, RAVER2.
  • Immunocytochemical staining of HeLa cells with RAVER2 antibody. Nuclei were stained blue with DAPI; RAVER2 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 μm.
  • Western blotting analysis using RAVER2 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with RAVER2 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
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Product Details

Uniprot No.
Target Names
RAVER2
Alternative Names
Ribonucleoprotein, PTB Binding 2; KIAA1579; Ribonucleoprotein PTB-Binding 2; Protein Raver-2; FLJ10770; Ribonucleoprotein, PTB-Binding 2
Species Reactivity
Human
Immunogen
Recombinant Human RAVER2 protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone No.
17D3
Purification Method
Affinity-chromatography
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Form
Liquid
Tested Applications
ELISA, WB, FC, ICC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
FC 1:200-1:2000
ICC 1:100-1:1000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
May bind single-stranded nucleic acids.
Gene References into Functions
  1. Deregulation of LMNB1 expression induces modified splicing of several genes, likely driven by raver-2 overexpression, and suggest that an alteration of mRNA processing could be a pathogenic mechanism in adult-onset autosomal dominant leukodystrophy. PMID: 25637521
  2. genetic polymorphism is ssociated with increased susceptibility for ulcerative colitis PMID: 22561236
  3. Together, our results suggest that regulation of human Raver2 expression involves TATA-less transcriptional activity. PMID: 22146317
Subcellular Location
Nucleus. Cytoplasm.
Database Links

HGNC: 25577

OMIM: 609953

KEGG: hsa:55225

STRING: 9606.ENSP00000360112

UniGene: Hs.591443

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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