Code | CSB-RA567010A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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IHC | 1:50-1:200 |
The SELPLG recombinant monoclonal antibody is produced through a four-step process: sequencing the SELPLG monoclonal antibody gene, cloning the gene into a plasmid vector, introducing the recombinant vector into a host cell line, and purifying the SELPLG recombinant monoclonal antibody from the cell culture supernatant via affinity chromatography. The SELPLG monoclonal antibody is derived from hybridomas that produce the SELPLG antibody. In the production of the SELPLG monoclonal antibody, a synthesized peptide derived from human SELPLG is used as the immunogen. The SELPLG recombinant monoclonal antibody has been validated for use in ELISA and IHC applications to detect human SELPLG protein.
The SELPLG protein, also known as P-selectin glycoprotein ligand-1, plays a crucial role in the recruitment and activation of leukocytes during inflammation and immune responses. It binds to P-selectin on activated endothelial cells and promotes leukocyte rolling and adhesion to the site of inflammation or injury. This protein is expressed on the surface of leukocytes, particularly on neutrophils, monocytes, and lymphocytes. It is also involved in other biological processes such as angiogenesis and tumor metastasis.
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