HEK293T/Mouse CDCP1 Stable Cell Line

Code	CSB-SC719456MO1
Size	1 vial contains approximately 5x10⁶ cells in 1 ml
Price	$5000
Image	Untransfected HEK293T cells (green line) and transfected Mouse Cdcp1 HEK293T stable cells (red line) were stained with anti-CDCP1 antibody (2µg/1*10⁶cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
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Target Background

Product Details

Uniprot No.

Q5U462

Growth Properties

Adherent

Selection Marker

Puromycin

Culture Medium

DMEM + 10% FBS + 2 μg/ml Puromycin

Alternative Names

CDCP1

Tag Info

N-terminal Flag-tagged

Buffer

35% FBS + 55% DMEM + 10% DMSO

Tested Applications

Binding assay by FACS and cell based ELISA.

Storage

Frozen in liquid nitrogen or -80°C

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
(From Uniprot)

May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.

Gene References into Functions

Results indicate Cdcp1 (CD318) as a ligand of T-cell differentiation antigen CD6 (CD6) and a potential target for the diagnosis and treatment of autoimmune diseases. PMID: 28760953
Trask loss enhances tumorigenic growth by liberating integrin signaling and growth factor receptor cross-talk in unanchored cells. PMID: 23243018
established mechanism for initiation of CDCP1-mediated signaling; demonstrated that processing of surface CDCP1 by extracellular serine proteases is prerequisite for CDCP1-dependent survival of cancer cells during metastasis; preventing cleavage of CDCP1 abrogated survival signaling associated with CDCP1 and induced PARP1 cleavage and PARP1-mediated apoptosis PMID: 22179830
CDCP1 may have a role in neoplasm metastasis; targeting it with a monoclonal antibody inhibits metastasis in a prostate cancer model PMID: 18483259

Subcellular Location

Cell membrane; Single-pass membrane protein.

Database Links

KEGG: mmu:109332

STRING: 10090.ENSMUSP00000042057

UniGene: Mm.27519

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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HEK293T/Mouse CDCP1 Stable Cell Line

Product Details

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Customer Reviews and Q&A

Target Background

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