Recombinant Chicken Syndecan-3(SDC3)

Code CSB-CF020890CH
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P26261
Storage Buffer Tris-based buffer,50% glycerol
Species Gallus gallus (Chicken)
Sequence QPWRNENYERPVDLEGSGDDDPFGDDELDDIYSGSGSGYFEQESGLETAVSLTTDTSVPLPTTVAVLPVTLVQPMATPFELFPTEDTSPEQTTSVLYIPKITEAPVIPSWKTTTASTTASDSPSTTSTTTTTAATTTTTTTTISTTVATSKPTTTQRFLPPFVTKAATTRATTLETPTTSIPETSVLTEVTTSRLVPSSTAKPRSLPKPSTSRTAEPTEKSTALPSSPTTLPPTEAPQVEPGELTTVLDSDLEVPTSSGPSGDFEIQEEEETTRPELGNEVVAVVTPPAAPGLGKNAEPGLIDNTIESGSSAAQLPQKNILERKEVLIAVIVGGVVGALFAAFLVMLLIYRMKKKDEGSYTLEEPKQANVTYQKPDKQEEFYA
Source in vitro E.coli expression system
Gene Names SDC3
Protein Names Recommended name: Syndecan-3
Expression Region 23-405
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Cell surface proteoglycan that may bear both heparan sulfate and chondroitin sulfate. The multiple functional domains provide potential sites for mediating the adhesive cell-matrix interactions and cytoskeletal reorganization involved in limb chondrogenesis. Interaction with other matrix ligands as well as phosphorylation and shedding of the ectodomain might be involved in cell shape changes that occur during chondrogenesis. Furthermore, shedding of the ectodomain might break the adhesive interactions that promoted condensation, thus facilitating the deposition of cartilage matrix molecules.
Subcellular Location Membrane, Single-pass type I membrane protein
Protein Families Syndecan proteoglycan family
Tissue Specificity Proximal chondrogenic central core of embryonic limb buds where cartilage differentiation is being initiated.
Database Links

KEGG: gga:396343

STRING: 9031.ENSGALP00000000792

UniGene: Gga.3136

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