Recombinant Horse Endothelin B receptor(EDNRB)

Code CSB-CF007404HO
Size Pls inquire other sizes
Source in vitro E.coli expression system

Product Details

Target Names EDNRB
Uniprot No. O62709
Species Equus caballus (Horse)
Expression Region 27-443
Target Protein Sequence EERRFPPARATPPLLGFEEIMTPPTKTSWPTGSNASVPRLSAPPQMPKAGRTAGAQRRTL PPPPCERTIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLAL GDLLHIIIDIPINVYKLLAEDWPFGVEMCKLVPFIQKASVGITVLSLCALSIDRYRAVAS WSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAVGFDMITADYKGSYLRICLLHPTQKTAF MQFYKNAKDWWLFSFYFCLPLAITAFFYTLETCEMLRKKSGMQIALNDHLKQRREVAKTV FCLVLVFALCWLPLHLSRILKHTLYDQNDPHRCELLSFLLVLEYIGINMASLNSCINPIA LYLVSKRFKNCFKWCLCCWCQSFEEKQSLEDKQSCLKFKANDHGYDNFRSSNKYSSS
Protein Length Full Length of Mature Protein
Tag Info The following tags are available.
N-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting
and FAQs
Protein FAQs
Storage Condition Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.
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Target Data

Function Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Involvement in disease Defects in EDNRB are a cause of overo lethal white syndrome (OLWS) also known as lethal white foal syndrome (LWFS). It is an inherited syndrome of foals born to American paint horse parents of the overo coat-pattern lineage. Affected foals are totally or almost totally white and die within days from complications due to intestinal aganglionosis.
Subcellular Location Cell membrane, Multi-pass membrane protein
Protein Families G-protein coupled receptor 1 family, Endothelin receptor subfamily, EDNRB sub-subfamily
Database Links

KEGG: ecb:100033875

STRING: 9796.ENSECAP00000022427

UniGene: Eca.13045

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