Recombinant Human Fatty acid desaturase 2(FADS2)

Code CSB-CF007960HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. O95864
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Sequence MGKGGNQGEGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVIGHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYLHK
Source in vitro E.coli expression system
Gene Names FADS2
Protein Names Recommended name: Fatty acid desaturase 2 EC= 1.14.19.-Alternative name(s): Delta(6) fatty acid desaturase Short name= D6D Short name= Delta(6) desaturase Short name= Delta-6 desaturase
Expression Region 1-444
Tag Info 10xHis-SUMO-tag
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18
Subcellular Location Endoplasmic reticulum membrane, Multi-pass membrane protein
Protein Families Fatty acid desaturase type 1 family
Tissue Specificity Expressed in a wide array of tissues, highest expression is found in liver followed by brain, lung, heart, and retina. A lower level is found in breast tumor when compared with normal tissues; lowest levels were found in patients with poor prognostic inde
Database Links

HGNC: 3575

OMIM: 606149

KEGG: hsa:9415

STRING: 9606.ENSP00000278840

UniGene: Hs.502745

Pathway PPAR signaling pathway

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