Recombinant Human Tryptophan 5-hydroxylase 2(TPH2)

Code CSB-CF809000HU
Product Type Transmembrane Protein
Size US$1235
Uniprot No. Q8IWU9
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Homo sapiens (Human)
Purity Greater than 90% as determined by SDS-PAGE.
Sequence MQPAMMMFSSKYWARRGFSLDSAVPEEHQLLGSSTLNKPNSGKNDDKGNKGSSKREAATESGKTAVVFSLKNEVGGLVKALRLFQEKRVNMVHIESRKSRRRSSEVEIFVDCECGKTEFNELIQLLKFQTTIVTLNPPENIWTEEEELEDVPWFPRKISELDKCSHRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMGYKYGQPIPRVEYTEEETKTWGVVFRELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSMFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYIRHGSDPLYTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKMNQYLGI
Research Area Neuroscience
Source in vitro E.coli expression system
Gene Names TPH2
Protein Names Neuronal tryptophan hydroxylase Tryptophan 5-monooxygenase 2
Expression Region 1-490aa
Tag Info N-terminal 6xHis-tagged
Mol. Weight 60.1kDa
Protein Description Full Length
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Involvement in disease Major depressive disorder (MDD); Attention deficit-hyperactivity disorder 7 (ADHD7)
Protein Families Biopterin-dependent aromatic amino acid hydroxylase family
Tissue Specificity Brain specific.
Database Links

HGNC: 20692

OMIM: 607478

KEGG: hsa:121278

STRING: 9606.ENSP00000329093

UniGene: Hs.736576

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