Recombinant Human Vesicle-associated membrane protein 4(VAMP4)

Code CSB-CF025783HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. O75379
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Sequence MPPKFKRHLNDDDVTGSVKSERRNLLEDDSDEEEDFFLRGPSGPRFGPRNDKIKHVQNQVDEVIDVMQENITKVIERGERLDELQDKSESLSDNATAFSNRSKQLRRQMWWRGCKIKAIMALVAAILLLVIIILIVMKYRT
Source in vitro E.coli expression system
Gene Names VAMP4
Protein Names Recommended name: Vesicle-associated membrane protein 4 Short name= VAMP-4
Expression Region 1-141
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule.
Subcellular Location Golgi apparatus, trans-Golgi network membrane, Single-pass type IV membrane protein
Protein Families Synaptobrevin family
Database Links

HGNC: 12645

OMIM: 606909

KEGG: hsa:8674

STRING: 9606.ENSP00000236192

UniGene: Hs.6651

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