VAMP4 Antibody

Datasheet

Code	CSB-PA025783LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: K562 whole cell lysate, RAW264.7 whole cell lysate All lanes: VAMP4 antibody at 4.3μg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 17 kDa Observed band size: 17 kDa
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) VAMP4 Polyclonal antibody

Uniprot No.

O75379

Target Names

VAMP4

Alternative Names

VAMP4; Vesicle-associated membrane protein 4; VAMP-4

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Vesicle-associated membrane protein 4 protein (1-115AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The VAMP4 Antibody (Product code: CSB-PA025783LA01HU) is Non-conjugated. For VAMP4 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA025783LB01HU	VAMP4 Antibody, HRP conjugated	ELISA
FITC	CSB-PA025783LC01HU	VAMP4 Antibody, FITC conjugated
Biotin	CSB-PA025783LD01HU	VAMP4 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule.

Gene References into Functions

Syntaxin 6 and VAMP4 colocalize to the chlamydial inclusion. PMID: 23798538
Data indicate that depletion of VAMP4, syntaxin 6, syntaxin 16, and Vti1a disrupted the Golgi ribbon structure. PMID: 23677696
colocalization of ATP11B with fluorescent cisplatin and with vesicular trafficking proteins, such as STX6 and VAMP4, strongly suggests that ATP11B contributes to secretory vesicular transport of cisplatin from Golgi to plasma membrane PMID: 23585472
The findings of this study suggested that VAMP4 and syb2 diverge functionally, traffic independently and support distinct forms of neurotransmission PMID: 22406549
VAMP7 is involved in many fusion processes and thus plays a more general function in NK-cell activity than VAMP4. PMID: 21805468

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Subcellular Location

Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Note=Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles.

Protein Families

Synaptobrevin family

Database Links

HGNC: 12645

OMIM: 606909

KEGG: hsa:8674

STRING: 9606.ENSP00000236192

UniGene: Hs.6651

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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