Recombinant Rat Hepatitis A virus cellular receptor 1 homolog(Havcr1)

Code CSB-CF010144RA
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. O54947
Storage Buffer Tris-based buffer,50% glycerol
Species Rattus norvegicus (Rat)
Sequence YEVVKGVVGHPVTIPCTYSTRGGITTTCWGRGQCPYSSCQNILIWTNGYQVTYRSSGRYNIKGRISEGDVSLTIENSVDSDSGLYCCRVEIPGWFNDQKMTFSLEVKPEIPTSPPTRPTTTRPTTTRPTTISTRSTHVPTSTRVSTSTPTPEQTQTHKPEITTFYAHETTAEVTETPSYTPADWNGTVTSSEEAWNNHTVRIPLRKPQRNPTKGFYVGMSVAALLLLLLASTVVVTRYIIIRKKMGSLSFVAFHVSKSRALQNAAIVHPRAEDNIYIIEDRSRGAE
Source in vitro E.coli expression system
Gene Names Havcr1
Protein Names Recommended name: Hepatitis A virus cellular receptor 1 homolog Short name= HAVcr-1 Alternative name(s): Kidney injury molecule 1 Short name= KIM-1 T cell immunoglobulin and mucin domain-containing protein 1 Short name= TIMD-1
Expression Region 22-307
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. May play a role in kidney injury and repair (By similarity).
Subcellular Location Membrane, Single-pass type I membrane protein
Protein Families Immunoglobulin superfamily, TIM family
Tissue Specificity Expressed at a low level in normal kidney but are increased dramatically in postischemic kidney. Expressed in proliferating bromodeoxyuridine-positive and dedifferentiated vimentin-positive epithelial cells in regenerating proximal tubules.
Database Links

KEGG: rno:286934

STRING: 10116.ENSRNOP00000009573

UniGene: Rn.11154

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