HAVCR1, also known as Hepatitis A virus cellular receptor 1, is commonly referred to as TIM - 1 (T - cell immunoglobulin and mucin domain - containing protein 1). It plays a pivotal role in the immune response. HAVCR1 can bind to phosphatidylserine on the surface of apoptotic cells, facilitating their clearance. It is involved in the T - cell activation and differentiation pathways.
Dysregulation of HAVCR1 has been associated with various diseases, such as autoimmune disorders and certain cancers. In the field of drug development, there is growing interest in targeting HAVCR1. Some monoclonal antibodies are under research to modulate its function, aiming to improve the treatment of related diseases.
Recombinant Human Hepatitis A virus cellular receptor 1 (HAVCR1), partial (CSB-MP010144HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
HAVCR1 Recombinant Monoclonal Antibody (CSB-RA974628A0HU)
Validated Data
Western Blot
Positive WB detected in: 293T whole cell lysate(30µg), NIH/3T3 whole cell lysate(30µg), JK whole cell lysate(30µg), MCF7 whole cell lysate(30µg), Hela whole cell lysate(30µg)
All lanes: HAVCR1 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/20000 dilution
Predicted band size: 50-55 kDa
Observed band size: 55 kDa
Exposure time:10s
Human Kidney injury molecule 1,Kim-1 ELISA Kit (CSB-E08807h)
Validated Data
Code: CSB-E08807h
Size: 96T,5×96T,10×96T
Sensitivity: 0.043 ng/mL
Detection Range: 0.312 ng/mL-20 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following HAVCR1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
HAVCR1 Antibodies for Mus musculus (Mouse)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA17109A0Rb | Havcr1 Antibody | Mouse | ELISA, IHC |
HAVCR1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA09995A0Rb | HAVCR1 Antibody | Human, Mouse | ELISA, WB, IHC |
CSB-PA090386 | HAVCR1 Antibody | Human | ELISA,IHC |
CSB-PA913997 | HAVCR1 Antibody | Human | ELISA,WB |
CSB-RA974628A0HU | HAVCR1 Recombinant Monoclonal Antibody | Human, Mouse | ELISA, WB |
CSB-RA010144MA1HU | HAVCR1 Recombinant Monoclonal Antibody | Human | ELISA, IHC |
HAVCR1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP010144HU CSB-EP010144HU CSB-BP010144HU CSB-EP010144HU-B |
Recombinant Human Hepatitis A virus cellular receptor 1 (HAVCR1), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
CSB-MP010144HU | Recombinant Human Hepatitis A virus cellular receptor 1 (HAVCR1), partial | Mammalian cell |
HAVCR1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP735580MO CSB-EP735580MO CSB-BP735580MO CSB-MP735580MO CSB-EP735580MO-B |
Recombinant Mouse Hepatitis A virus cellular receptor 1 homolog (Havcr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP735580MO | Recombinant Mouse Hepatitis A virus cellular receptor 1 homolog (Havcr1), partial | E.coli |
HAVCR1 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-CF010144RA | Recombinant Rat Hepatitis A virus cellular receptor 1 homolog (Havcr1) | in vitro E.coli expression system |
CSB-YP010144RA1 CSB-EP010144RA1 CSB-BP010144RA1 CSB-MP010144RA1 CSB-EP010144RA1-B |
Recombinant Rat Hepatitis A virus cellular receptor 1 homolog (Havcr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
HAVCR1 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
Code | Product Name | Source |
---|---|---|
CSB-CF010144DSU | Recombinant Chlorocebus aethiops Hepatitis A virus cellular receptor 1 (HAVCR1) | in vitro E.coli expression system |
CSB-YP010144DSU1 CSB-EP010144DSU1 CSB-BP010144DSU1 CSB-MP010144DSU1 CSB-EP010144DSU1-B |
Recombinant Chlorocebus aethiops Hepatitis A virus cellular receptor 1 (HAVCR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
HAVCR1 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E08807h | Human Kidney injury molecule 1,Kim-1 ELISA Kit | serum, urine, tissue homogenates | 0.043 ng/mL |
HAVCR1 ELISA Kit for Monkey
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL010144RH | Monkey hepatitis A virus cellular receptor 1/KIM1(HAVCR1) ELISA kit | serum, urine | 0.078 ng/mL |
HAVCR1 ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E08809m | Mouse Kidney injury molecule 1,Kim-1 ELISA Kit | serum, plasma, tissue homogenates, urine | 0.225 ng/mL |
HAVCR1 ELISA Kit for Rattus norvegicus (Rat)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E08808r | Rat Kidney injury molecule 1,Kim-1 ELISA Kit | serum, plasma, urine | 0.228 ng/mL |