GPR20 (US10906974 Biosimilar) Recombinant Monoclonal Antibody

Code CSB-RA860774MB1HU
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Product Details

Uniprot No.
Target Names
Alternative Names
G protein coupled receptor 20 antibody; G-protein coupled receptor 20 antibody; Gpr20 antibody; GPR20_HUMAN antibody
Species Reactivity
Human, Macaca fascicularis
Immunogen
Recombinant Human GPR20 protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Monoclonal
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.159
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Notes
Validation Status
Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
Guaranteed Quality
① Antibody purity > 95% tested by SDS-PAGE.
② Endotoxin level < 0.1EU/ug tested by LAL method.
Lead Time
In stock
Usage
It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.

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Target Background

Function
Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP.
Gene References into Functions
  1. GPR20 constitutively activates G(i) proteins without ligand stimulation PMID: 18347022
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 1 family
Tissue Specificity
Ubiquitous with highest levels in intestinal tissues. In the brain detected in thalamus, putamen, and caudate, but not in frontal cortex, pons and hypothalamus.
Database Links

HGNC: 4475

OMIM: 601908

KEGG: hsa:2843

STRING: 9606.ENSP00000366970

UniGene: Hs.152432

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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