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ITPRIPL1 (CN113416253A Biosimilar) Recombinant Monoclonal Antibody

Datasheet
Code CSB-RA756966MB1HU
Size US$9799
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Product Details

Uniprot No.
Q6GPH6
Target Names
ITPRIPL1
Alternative Names
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 antibody, ITPRIPL1 antibody, KIAA1754L antibody
Species Reactivity
Human
Immunogen
Recombinant Human ITPRIPL1 protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Monoclonal
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
0.01M PBS，pH7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Notes
Validation Status
Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
Guaranteed Quality
① Antibody purity > 95% tested by SDS-PAGE.
② Endotoxin level < 0.1EU/ug tested by LAL method.
Lead Time
In stock
Description

This recombinant monoclonal antibody targets ITPRIPL1 (Inositol 1,4,5-Trisphosphate Receptor Interacting Protein Like 1), a member of the ITPRIP family of proteins involved in intracellular calcium signaling regulation. ITPRIPL1 functions as a modulator of inositol 1,4,5-trisphosphate receptor (IP3R) activity, influencing calcium release from intracellular stores and participating in various cellular processes including signal transduction, cell proliferation, and apoptosis. This protein has been implicated in neurological function and cellular stress responses, making it relevant to studies of calcium homeostasis disorders and neurodegenerative conditions.

Developed as a research-grade biosimilar to the reference antibody described in patent CN113416253A, this antibody provides researchers with a reliable tool for investigating ITPRIPL1 expression, localization, and functional roles in various biological contexts. It is suitable for studies exploring calcium signaling pathways, protein-protein interactions involving IP3 receptors, and the molecular mechanisms underlying ITPRIPL1-related cellular processes. This reagent supports investigations in cell biology, neuroscience, and signal transduction research.

Usage
It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.

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ITPRIPL1 Antibodies

ITPRIPL1 Proteins

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Target Background

Subcellular Location
Membrane; Single-pass type I membrane protein.
Protein Families
ITPRIP family
Database Links

HGNC: 29371

KEGG: hsa:150771

STRING: 9606.ENSP00000355121

UniGene: Hs.65009

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