The gene Itpripl1 encodes the protein ITPR-interacting protein-like 1. It doesn't have well - known common aliases yet. This protein is involved in the regulation of intracellular calcium signaling. It interacts with inositol trisphosphate receptors (IP3Rs), which play a central role in releasing calcium from the endoplasmic reticulum.
Regarding its related aspects, abnormal function of Itpripl1 may lead to disruptions in calcium - mediated cellular processes, potentially contributing to neurological and cardiovascular diseases. As for drug development, research is in its early stages, focusing on understanding its precise role to identify potential drug targets for related disorders.
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human ITPRIPL1 at 2 μg/ml can bind Anti-ITPRIPL1 recombinant antibody (CSB-RA756966MA1HU). The EC50 is 6.537-7.663 ng/mL.
ITPRIPL1 Recombinant Monoclonal Antibody (CSB-RA756966MA1HU)
Validated Data
The Binding Activity of Macaca fascicularis ITPRIPL1 with Anti-ITPRIPL1 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis ITPRIPL1 (CSB-MP6125MOV) at 2 μg/mL can bind Anti-ITPRIPL1 recombinant antibody. The EC50 is 3.759-4.428 ng/mL.
The Binding Activity of Human ITPRIPL1 with Anti-ITPRIPL1 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ITPRIPL1 (CSB-MP756966HU) at 2 μg/mL can bind Anti-ITPRIPL1 recombinant antibody. The EC50 is 6.537-7.663 ng/mL.
The Binding Activity of Mouse Itpripl1 with Anti-ITPRIPL1 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse Itpripl1 (CSB-MP011916MO1) at 2 μg/mL can bind Anti-ITPRIPL1 recombinant antibody. The EC50 is 0.7534-0.9877 ng/mL.
The following ITPRIPL1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ITPRIPL1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-RA756966MA1HU | ITPRIPL1 Recombinant Monoclonal Antibody | Human, Macaca fascicularis | ELISA |
ITPRIPL1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP756966HU CSB-EP756966HU CSB-BP756966HU CSB-MP756966HU CSB-EP756966HU-B |
Recombinant Human Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 (ITPRIPL1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-MP756966HU | Recombinant Human Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 (ITPRIPL1), partial (Active) | Mammalian cell |