Useful Resources

Transmembrane proteins are located at the interface between cells and the outside world, mediating the signal transduction between cells and the outside world, and performing many important cellular biological functions. For example, it is a receptor for various signaling molecules, hormones and other substrates; it is involved in the exchange of substances, energy and signal between the inside and outside of the cell membrane; it constitutes a channel for various ion transmembranes, which inputs nutrients and some inorganic electrolytes into cells, and discharges toxic or useless metabolites into cells.

Aquaporin

• The Nature of Detergent and Its Application in Membrane Proteins
• The Application of Nanodiscs in Membrane Proteins
• Transmembrane protein series one: Aquaporin

Ion Channels

• A Switch that Controls the Entry and Exit of Ions
• Transmembrane protein series two: Ion Channels

G protein-Coupled Receptor

• G protein-Coupled Receptor - Targets for Drug Therapy
• Transmembrane protein series three: G protein-Coupled Receptor

ATP-binding Cassette

• A Transport Machine -- ATP-binding Cassette
• Transmembrane protein series four: ATP-binding cassette transporters

Human Leukocyte Antigen

• Human Leukocyte Antigen: Distinguish between Friend and Foe
• Transmembrane protein series five: Human leukocyte antigen (HLA)

Transmembrane protein products expressed by cell-free expression systems can be used to study the functions of transmembrane proteins. The integration of transmembrane proteins into vesicles for structural and functional studies is a hot topic in membrane protein research.

According to its structure, transmembrane proteins can be classified into alpha helix and β - barrel membrane proteins. For details, please refer to the article: A Resume for Transmembrane Proteins.