Chimeric antigen receptor (CAR) T-cell therapy is a kind of cancer treatment that uses cells from your own immune system. Doctors take a type of white blood cell from your body and genetically change the cells in a lab so they can better find your cancer. Then millions of these target-seeking cells are put back into your body. CAR-T Cell Therapy Targets refer to targets involved in CAR-T cell therapy. More information about CAR-T Cell Therapy, you can click the following link: https://www.cusabio.com/car-t-cell-therapy.html.
CUSABIO has successfully developed over several active proteins, covering the hottest investigational CAR-T cell therapy targets. All of these proteins with high purity and high binding activity. Therefore, CAR-T cell therapy target proteins in CUSABIO are the first choice for your scientific research.
Regard reading: CAR-T Cell Therapy- An Useful Treatment To Cancer.
High Purity
The purity of Recombinant Human PDL1 (CSB-MP878942HU1) is >95% as determined by SDS-PAGE.
The purity of Recombinant Human CD22 (CSB-MP004900HU) is >94% as determined by SDS-PAGE.
Highly Identical Protein Sequences
Based on the SEQUEST from database of Mammalian Cell host and target protein, the LC-MS/MS Analysis result of CSB-MP007479HU could indicate that this peptide derived from Mammalian Cell-expressed Recombinant Human EGFR.
Multi-validated Activity
CUSABIO: EC50=1.404-1.905 ng/ml
VS
XX company: EC50=1.720-2.184 ng/ml
CUSABIO: KD:1.66e-7 M
VS
XX company: 1.19e-8 M
Gene Name | Uniprot ID | Code | Product Name | Source |
---|---|---|---|---|
CD19 | P15391 | CSB-AP005061HU | Recombinant Human B-lymphocyte antigen CD19 (CD19), partial (Active) |
Mammalian cell |
EGFR | P00533 | CSB-MP007479HU | Recombinant Human Epidermal growth factor receptor (EGFR), partial (Active) |
Mammalian cell |
TNFRSF17 | Q02223 | CSB-MP023974HU1 | Recombinant Human Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), partial (Active) |
Mammalian cell |
MSLN | Q13421 | CSB-MP015044HUc9 | Recombinant Human Mesothelin (MSLN), partial (Active) |
Mammalian cell |
CD274 | Q9NZQ7 | CSB-MP878942HU1 | Recombinant Human Programmed cell death 1 ligand 1 (CD274), partial (Active) |
Mammalian cell |
KLRK1 | P26718 | CSB-MP012474HU1 | Recombinant Human NKG2-D type II integral membrane protein (KLRK1), partial (Active) |
Mammalian cell |
CD22 | P20273 | CSB-MP004900HU | Recombinant Human B-cell receptor CD22 (CD22), partial (Active) |
Mammalian cell |