AATK Antibody

Code CSB-PA046504
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA046504(AATK Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA046504(AATK Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
AATK
Alternative Names
AATK antibody; AATYK antibody; AATYK1 antibody; Apoptosis associated tyrosine kinase antibody; Apoptosis-associated tyrosine kinase antibody; Brain apoptosis associated tyrosine kinase antibody; Brain apoptosis-associated tyrosine kinase antibody; CDK5 binding protein antibody; CDK5-binding protein antibody; KIAA0641 antibody; Lemur tyrosine kinase 1 antibody; LMR1 antibody; LMTK1 antibody; LMTK1_HUMAN antibody; p35 binding protein antibody; p35-binding protein antibody; p35BP antibody; Serine/threonine protein kinase LMTK1 antibody; Serine/threonine-protein kinase LMTK1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide of Human AATK
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:10000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be involved in neuronal differentiation.
Gene References into Functions
  1. ATKK was validated as a target gene of miR-558, and upregulation of miR-558 was observed in radioresistant lung cancer cells. Additionally, ectopic overexpression of ATKK partially but significantly reduced the miR-558-induced radioresistance. PMID: 27485693
  2. Apoptosis-associated tyrosine kinase is a Cdk5 activator p35 binding protein. PMID: 14521924
  3. This paper deals with the mouse ortholog. PMID: 17651901
Subcellular Location
Membrane; Single-pass type I membrane protein. Cytoplasm. Cytoplasm, perinuclear region. Note=Predominantly perinuclear.
Protein Families
Protein kinase superfamily, Tyr protein kinase family
Tissue Specificity
Expressed in brain.
Database Links

HGNC: 21

OMIM: 605276

KEGG: hsa:9625

STRING: 9606.ENSP00000324196

UniGene: Hs.514575

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