ACOT11 Antibody

Datasheet

Code	CSB-PA908870
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA908870(ACOT11 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA908870(ACOT11 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200) Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human fetal kidney tissue, Human fetal lung tissue, Primary antibody: CSB-PA908870(ACOT11 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 90 seconds
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Product Details
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Target Background

Product Details

Uniprot No.

Q8WXI4

Target Names

ACOT11

Alternative Names

ACO11_HUMAN antibody; ACOT 11 antibody; ACOT11 antibody; Acyl CoA thioester hydrolase 11 antibody; Acyl CoA thioesterase 11 antibody; Acyl coenzyme A thioesterase 11 antibody; Acyl-CoA thioester hydrolase 11 antibody; Acyl-CoA thioesterase 11 antibody; Acyl-coenzyme A thioesterase 11 antibody; Adipose associated thioesterase antibody; Adipose-associated thioesterase antibody; BFIT 1 antibody; BFIT 2 antibody; BFIT antibody; BFIT1 antibody; BFIT2 antibody; Brown fat inducible thioesterase antibody; Brown fat-inducible thioesterase antibody; KIAA0707 antibody; OTTHUMP00000046722 antibody; StAR related lipid transfer (START) domain containing 14 antibody; STARD 14 antibody; STARD14 antibody; START domain containing 14 antibody; THEA antibody; THEM 1 antibody; THEM1 antibody; Thioesterase adipose associated antibody; Thioesterase superfamily member 1 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Fusion protein of Human ACOT11

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
WB	1:200-1:1000
IHC	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.

Gene References into Functions

The N-terminal region of human fat inducible thioesterase variant 2 constitutes a mitochondrial location signal sequence, which undergoes mitochondrion-dependent posttranslational cleavage. PMID: 22897136
BFIT supports the transition of thermogenic brown adipose tissue towards increased metabolic activity, probably through alteration of intracellular fatty acyl-CoA concentration. PMID: 11696000

Subcellular Location

Mitochondrion matrix. Cytoplasm.

Tissue Specificity

Isoform 1 is predominantly expressed in skeletal muscle, liver, testis, stomach, spleen, lung and brain. Isoform 2 is predominantly expressed in kidney, uterus, hibernoma and white adipose tissue.

Database Links

HGNC: 18156

OMIM: 606803

KEGG: hsa:26027

STRING: 9606.ENSP00000360366

UniGene: Hs.745173

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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