ACOT7 Antibody

Code CSB-PA001169GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
ACOT7
Alternative Names
ACH1 antibody; ACOT 7 antibody; ACOT7 antibody; ACT antibody; Acyl CoA thioesterase 7 antibody; Acyl CoA thioesterase long chain antibody; Acyl-CoA thioesterase 7 antibody; BACH antibody; BACH_HUMAN antibody; Brain acyl CoA hydrolase antibody; Brain acyl-CoA hydrolase antibody; CTE-II antibody; CTE-IIa antibody; Cytosolic acyl coenzyme A thioester hydrolase antibody; hBACH antibody; LACH antibody; LACH1 antibody; Long chain acyl-CoA thioester hydrolase antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human ACOT7
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Preferentially hydrolyzes palmitoyl-CoA, but has a broad specificity acting on other fatty acyl-CoAs with chain-lengths of C8-C18. May play an important physiological function in brain.
Gene References into Functions
  1. PKCzeta was specifically involved in ACOT7 depletion-mediated cell cycle arrest as an upstream molecule of the p53-p21 signaling pathway in MCF7 human breast carcinoma and A549 human lung carcinoma cells. PMID: 28518146
  2. WIG1 governs the miRNA-dependent and the miRNA-independent recruitment of AGO2 to lower the stability of and suppress the translation of ACOT7 mRNA. PMID: 28472401
  3. the human BACH gene can express long-chain acyl-CoA hydrolase activity in multiple intracellular compartments by generating BACH isoforms with differential localization signals to affect various cellular functions that involve acyl-CoAs PMID: 12435388
  4. BACH was deranged in hippocampus of mesial temporal lobe epilepsy patients. PMID: 15592755
Subcellular Location
[Isoform 4]: Cytoplasm, cytosol.; [Isoform 6]: Cytoplasm, cytosol.; [Isoform 1]: Mitochondrion.; [Isoform 5]: Mitochondrion.
Tissue Specificity
Isoform 4 is expressed exclusively in brain.
Database Links

HGNC: 24157

OMIM: 602587

KEGG: hsa:11332

STRING: 9606.ENSP00000367086

UniGene: Hs.126137

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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