ANO7 Antibody

Datasheet

Code	CSB-PA020234
Size	US$119
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Image	Western Blot analysis of 3T3 cells using NGEP Polyclonal Antibody
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q6IWH7

Target Names

ANO7

Alternative Names

Ano7 antibody; ANO7_HUMAN antibody; Anoctamin 7 antibody; Anoctamin-7 antibody; D TMPP antibody; D-TMPP antibody; Dresden transmembrane protein of the prostate antibody; DTMPP antibody; IPCA 5 antibody; IPCA-5 antibody; IPCA5 antibody; New gene expressed in prostate antibody; NGEP antibody; PCANAP5 antibody; PCANAP5L antibody; Prostate cancer associated protein 5 antibody; Prostate cancer-associated protein 5 antibody; TMEM16G antibody; Transmembrane protein 16G antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from the C-terminal region of Human NGEP.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, IHC, IF, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:100-1:300
IF	1:200-1:1000
ELISA	1:20000

Protocols

Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide. Does not exhibit calcium-activated chloride channel (CaCC) activity. May play a role in cell-cell interactions.

Gene References into Functions

high level of NGEP expression could be associated with good prognosis in prostate cancer PMID: 25808443
NGEP protein is widely expressed in low-grade to high-grade prostate adenocarcinomas as well as benign prostate tissues, and the intensity of expression is inversely proportional to the level of malignancy. PMID: 23955683
expressed only in prostate and prostate camcer is a promising target for the antibody-based therapies of prostate cancer PMID: 14981236
Complete coding sequence of TMEM16G cDNA was determined by assembling 25 exons of TMEM16G gene PMID: 15375614
description of the novel prostate-restricted molecule D-TMPP widely expressed in prostate cancer tissues PMID: 15761874
NGEP is a glycoprotein with predicted glycosylation sites at N809 and N824. When these residues were converted to glutamine, glycosylation was abolished, confirming that the residues are extracellular PMID: 18676855
NGEP is a potential target for T cell-mediated immunotherapy of prostate cancer. PMID: 19495750

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Subcellular Location

[Isoform 1]: Cell membrane; Multi-pass membrane protein. Cell junction. Endoplasmic reticulum.; [Isoform 2]: Cytoplasm, cytosol.

Protein Families

Anoctamin family

Tissue Specificity

Specifically expressed in epithelial cells of the prostate (at protein level).

Database Links

HGNC: 31677

OMIM: 605096

KEGG: hsa:50636

STRING: 9606.ENSP00000274979

UniGene: Hs.163909

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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