ARMCX1 Antibody

Datasheet

Code	CSB-PA878960LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA878960LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ARMCX1 Polyclonal antibody

Uniprot No.

Q9P291

Target Names

ARMCX1

Alternative Names

ARMCX 1 antibody; AD032 antibody; ALEX1 antibody; ARM protein lost in epithelial cancers on chromosome X 1 antibody; Arm protein lost in epithelial cancers X chromosome 1 antibody; Armadillo repeat containing X linked 1 antibody; Armadillo repeat containing X linked protein 1 antibody; Armadillo repeat-containing X-linked protein 1 antibody; ARMCX1 antibody; ARMX1_HUMAN antibody; Protein ALEX1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Armadillo repeat-containing X-linked protein 1 protein (29-300AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The ARMCX1 Antibody (Product code: CSB-PA878960LA01HU) is Non-conjugated. For ARMCX1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA878960LB01HU	ARMCX1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA878960LC01HU	ARMCX1 Antibody, FITC conjugated
Biotin	CSB-PA878960LD01HU	ARMCX1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Regulates mitochondrial transport during axon regeneration. Increases the proportion of motile mitochondria by recruiting stationary mitochondria into the motile pool. Enhances mitochondria movement and neurite growth in both adult axons and embryonic neurons. Promotes neuronal survival and axon regeneration after nerve injury. May link mitochondria to the Trak1-kinesin motor complex via its interaction with MIRO1.

Gene References into Functions

It is suggested that the ALEX1 protein is associated with tumorigenesis in cervical cancer and we speculate that the ALEX1 may plays a role as an oncogene in cervical cancer. PMID: 26464700
ALEX1 is a crucial tumor suppressor gene involved in cell proliferation and apoptosis in breast cancer. PMID: 25921134
Findings suggest that overexpression of ALEX1 (armadillo repeat containing, X-linked [ARMCX]) plays a negative role in colorectal tumorigenesis. PMID: 22494058
Human Arm protein lost in epithelial cancers, on chromosome X 1 (ALEX1) gene is transcriptionally regulated by CREB and Wnt/beta-catenin signaling. PMID: 20398052

Subcellular Location

Mitochondrion. Mitochondrion outer membrane; Single-pass membrane protein.

Protein Families

Eutherian X-chromosome-specific Armcx family

Tissue Specificity

Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes. Not or reduced expressed in lung, prostate, colon, pancreas and ovarian carci

Database Links

HGNC: 18073

OMIM: 300362

KEGG: hsa:51309

STRING: 9606.ENSP00000361917

UniGene: Hs.9728

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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