Recombinant Human Armadillo repeat-containing X-linked protein 1 (ARMCX1), partial

Code CSB-YP878960HU
MSDS
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Source Yeast
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Code CSB-EP878960HU
MSDS
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Source E.coli
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Code CSB-EP878960HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP878960HU
MSDS
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Source Baculovirus
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Code CSB-MP878960HU
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
ARMCX1
Uniprot No.
Alternative Names
ARMCX 1; AD032; ALEX1; ARM protein lost in epithelial cancers on chromosome X 1; Arm protein lost in epithelial cancers X chromosome 1; Armadillo repeat containing X linked 1; Armadillo repeat containing X linked protein 1; Armadillo repeat-containing X-linked protein 1; ARMCX1; ARMX1_HUMAN; Protein ALEX1
Species
Homo sapiens (Human)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Regulates mitochondrial transport during axon regeneration. Increases the proportion of motile mitochondria by recruiting stationary mitochondria into the motile pool. Enhances mitochondria movement and neurite growth in both adult axons and embryonic neurons. Promotes neuronal survival and axon regeneration after nerve injury. May link mitochondria to the Trak1-kinesin motor complex via its interaction with MIRO1.
Gene References into Functions
  1. It is suggested that the ALEX1 protein is associated with tumorigenesis in cervical cancer and we speculate that the ALEX1 may plays a role as an oncogene in cervical cancer. PMID: 26464700
  2. ALEX1 is a crucial tumor suppressor gene involved in cell proliferation and apoptosis in breast cancer. PMID: 25921134
  3. Findings suggest that overexpression of ALEX1 (armadillo repeat containing, X-linked [ARMCX]) plays a negative role in colorectal tumorigenesis. PMID: 22494058
  4. Human Arm protein lost in epithelial cancers, on chromosome X 1 (ALEX1) gene is transcriptionally regulated by CREB and Wnt/beta-catenin signaling. PMID: 20398052
Subcellular Location
Mitochondrion. Mitochondrion outer membrane; Single-pass membrane protein.
Protein Families
Eutherian X-chromosome-specific Armcx family
Tissue Specificity
Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes. Not or reduced expressed in lung, prostate, colon, pancreas and ovarian carci
Database Links

HGNC: 18073

OMIM: 300362

KEGG: hsa:51309

STRING: 9606.ENSP00000361917

UniGene: Hs.9728

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