ATG9B Antibody

Datasheet

Code	CSB-PA721119ESR1HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA721119ESR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA721119ESR1HU at dilution of 1:100
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ATG9B Polyclonal antibody

Uniprot No.

Q674R7

Target Names

ATG9B

Alternative Names

APG9 like 2 antibody; APG9-like 2 antibody; Apg912 antibody; APG9L2 antibody; Apgdc2 antibody; ATG9 autophagy related 9 homolog B (S. cerevisiae) antibody; Atg9b antibody; ATG9B_HUMAN antibody; Autophagy 9 like 2 protein antibody; Autophagy related protein 9B antibody; Autophagy-related protein 9B antibody; Endothelial nitric oxide synthase antisense antibody; eONE antibody; Gm574 antibody; Nitric oxide synthase 3 antisense antibody; Nitric oxide synthase 3 overlapping antisense gene protein antibody; Nitric oxide synthase 3-overlapping antisense gene protein antibody; NOS3AS antibody; Protein sONE antibody; SONE antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Autophagy-related protein 9B protein (715-924AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Phospholipid scramblase involved in autophagy by mediating autophagosomal membrane expansion. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 (ATG2A or ATG2B) from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion. In addition to autophagy, also plays a role in necrotic cell death.

Gene References into Functions

there is a close relationship between CRP and ATG9B in clear cell renal cell carcinomacarcinogenesis. PMID: 28923830
This study highlights the transcriptional inactivation mechanisms of ATG2B, ATG4D, ATG9A and ATG9B promoter methylation status and the possible origin of autophagy signal pathway repression in invasive ductal carcinomas. PMID: 27265029
Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
Observational study of gene-disease association. (HuGE Navigator) PMID: 19423540
Observational study of gene-disease association. (HuGE Navigator) PMID: 20406964
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 20416077
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 20438785
The role of Atg9 trafficking in yeast and mammalian autophagy, is summarised. PMID: 20083107
Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and genetic testing. (HuGE Navigator) PMID: 19948975
APG9L2 is highly expressed in placenta (trophoblast cells) and pituitary gland of adult tissues. PMID: 15755735
Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 19423521
Observational study of gene-disease association. (HuGE Navigator) PMID: 19197948

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Subcellular Location

Preautophagosomal structure membrane; Multi-pass membrane protein.

Protein Families

ATG9 family

Tissue Specificity

Highly expressed in placenta (trophoblast cells) and pituitary gland. Not expressed in vascular endothelial.

Database Links

HGNC: 21899

OMIM: 612205

KEGG: hsa:285973

UniGene: Hs.707300

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Autophagy Mitophagy

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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