Recombinant Human Autophagy-related protein 9B(ATG9B) ,partial

Code CSB-YP721119HU
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Source Yeast
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Code CSB-EP721119HU
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Source E.coli
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Code CSB-EP721119HU-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP721119HU
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Source Baculovirus
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Code CSB-MP721119HU
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Source Mammalian cell
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Product Details

Purity >85% (SDS-PAGE)
Target Names ATG9B
Uniprot No. Q674R7
Alternative Names APG9 like 2; APG9-like 2; Apg912; APG9L2; Apgdc2; ATG9 autophagy related 9 homolog B (S. cerevisiae); Atg9b; ATG9B_HUMAN; Autophagy 9 like 2 protein; Autophagy related protein 9B; Autophagy-related protein 9B; Endothelial nitric oxide synthase antisense; eONE; Gm574; Nitric oxide synthase 3 antisense; Nitric oxide synthase 3 overlapping antisense gene protein; Nitric oxide synthase 3-overlapping antisense gene protein; NOS3AS; Protein sONE; SONE
Species Homo sapiens (Human)
Protein Length Partial
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting
and FAQs
Protein FAQs
Storage Condition Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

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Target Data

Function Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle (By similarity).
Gene References into Functions
  1. there is a close relationship between CRP and ATG9B in clear cell renal cell carcinomacarcinogenesis. PMID: 28923830
  2. This study highlights the transcriptional inactivation mechanisms of ATG2B, ATG4D, ATG9A and ATG9B promoter methylation status and the possible origin of autophagy signal pathway repression in invasive ductal carcinomas. PMID: 27265029
  3. Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
  4. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
  5. Observational study of gene-disease association. (HuGE Navigator) PMID: 19423540
  6. Observational study of gene-disease association. (HuGE Navigator) PMID: 20406964
  7. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 20416077
  8. Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) PMID: 20438785
  9. The role of Atg9 trafficking in yeast and mammalian autophagy, is summarised. PMID: 20083107
  10. Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and genetic testing. (HuGE Navigator) PMID: 19948975
  11. APG9L2 is highly expressed in placenta (trophoblast cells) and pituitary gland of adult tissues. PMID: 15755735
  12. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 19423521
  13. Observational study of gene-disease association. (HuGE Navigator) PMID: 19197948

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Subcellular Location Cytoplasmic vesicle, autophagosome membrane, Multi-pass membrane protein
Protein Families ATG9 family
Tissue Specificity Highly expressed in placenta (trophoblast cells) and pituitary gland. Not expressed in vascular endothelial.
Database Links

HGNC: 21899

OMIM: 612205

KEGG: hsa:285973

UniGene: Hs.707300

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